Enzyme Kinetics at the Molecular Level
نویسندگان
چکیده
منابع مشابه
The Kinetics of Enzyme Mixtures
Even purified enzyme preparations are often heterogeneous. For example, preparations of aspartate aminotransferase or cytochrome oxidase can consist of several different forms of the enzyme. For this reason we consider how different the kinetics of the reactions catalysed by a mixture of forms of an enzyme must be to provide some indication of the characteristics of the species present. Based...
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We re-visit previous analyses of the classical Michaelis-Menten substrate-enzyme reaction and, with the aid of the reverse quasi-steady-state assumption, we challenge the approximation d[C]/dt approximately 0 for the basic enzyme reaction at high enzyme concentration. For the first time, an approximate solution for the concentrations of the reactants uniformly valid in time is reported. Numeric...
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The logistic temporal solution of the generalized Michaelis-Menten kinetics is employed to provide a quantum basis for the tunneling time and energy evaluations of Brownian enzymic reactions. The monosubstrate and mixed inhibition cases are treated and the associated quantum diagrams of the reaction mechanisms are depicted in terms of intermediate enzyme complexes. The methodology is suited for...
متن کاملthe kinetics of enzyme mixtures
even purified enzyme preparations are often heterogeneous. for example, preparations of aspartate aminotransferase or cytochrome oxidase can consist of several different forms of the enzyme. for this reason we consider how different the kinetics of the reactions catalysed by a mixture of forms of an enzyme must be to provide some indication of the characteristics of the species present. based...
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ژورنال
عنوان ژورنال: Resonance
سال: 2019
ISSN: 0971-8044,0973-712X
DOI: 10.1007/s12045-019-0781-9